Why do people take L-tryptophan?

L-tryptophan Powder

Product Name: L-Tryptophan

CAS #: 73-22-3

MW: 204.23 g/mol

Grade: Food Grade

Storage/Handling: Store at room temperature.

Formula: C11H12N2O2

Color/Purity: White to light yellow crystalline powder.

Storage/Handling: Protect from light.


L-Tryptophan is an essential amino acid that is necessary for making proteins. It is naturally found in red meat, poultry, eggs, and dairy.

L-tryptophan is important for many organs in the body. L-tryptophan is not made by the body and must be consumed from the diet. After absorbing L-tryptophan from food, the body converts some of it to 5-HTP and then to serotonin. Serotonin is a hormone that transmits signals between nerve cells. Changes in serotonin levels in the brain can affect mood.

People use L-tryptophan for severe PMS symptoms, depression, insomnia, and many other conditions, but there is no good scientific evidence to support any of these uses.

L-tryptophan benefit
L-tryptophan benefit1
L-tryptophan benefits2

L-tryptophan is known for its numerous benefits and effects on the body. One of its primary functions is as a precursor to serotonin, a neurotransmitter that regulates mood, sleep, and appetite. By increasing serotonin levels, L-tryptophan can help improve mood, reduce anxiety and depression, and promote better sleep quality.

Moreover, L-tryptophan has been found to have a positive impact on cognitive function. It is involved in the synthesis of another neurotransmitter called melatonin, which regulates the sleep-wake cycle. By promoting the production of melatonin, L-tryptophan can enhance sleep quality and regulate circadian rhythms.

In addition to its effects on mood and sleep, L-tryptophan has been studied for its potential benefits in managing certain medical conditions. It has been found to be effective in reducing symptoms of premenstrual syndrome (PMS) and improving symptoms of seasonal affective disorder (SAD). L-tryptophan supplementation has also shown promise in reducing symptoms of attention deficit hyperactivity disorder (ADHD) and promoting weight loss by reducing appetite.

Due to its various benefits and effects on the body, L-tryptophan is commonly used as a dietary supplement. It is available in capsule or tablet form and can be purchased over-the-counter. However, it is important to consult with a healthcare professional before starting any supplementation to determine the appropriate dosage and ensure it is safe for individual use.

How is it typically used?

L-tryptophan application

L-tryptophan supplements have most often been used by adults in doses of 60 mg by mouth daily for 16 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Keep in mind that some dietary supplement products might not list L-tryptophan separately on the label. Instead, it might be listed under niacin. Niacin is measured in niacin equivalents (NE). 60 mg of L-tryptophan is the same as 1 mg NE.

In conclusion, L-tryptophan is an essential amino acid that plays a vital role in protein synthesis and neurotransmitter production. Its benefits include improving mood, promoting better sleep, enhancing cognitive function, and potentially managing certain medical conditions. As a dietary supplement, L-tryptophan can be used to support overall well-being, but it is important to seek professional advice before starting any supplementation.