The Surprising Benefits of Grape Skin Extract


In the pursuit of optimal health and wellness, people often turn to natural solutions that are scientifically proven to support their health. One solution that has gained a lot of attention in recent years is grape skin extract. Grape skin extract is also known as grape skin red, ENO. Grape skin pigment is a natural edible pigment extracted from grape skin, red to dark purple in color, belonging to natural anthocyanin pigments, safe, Chemicalbook non-toxic and contains certain nutrients, with antioxidant and free radical scavenging effects, and has certain medicinal and health care value. Grape skin pigment can be used as colorant for food and cosmetics. With its abundance of pharmacologically active substances and numerous health benefits, grape skin extract has become a sought-after supplement for individuals seeking to enhance their overall health.

Aogubio, a company specialized in the production and sale of pharmacologically active substances, raw materials and plant extracts, recognized the great potential of grape skin extracts. Committed to providing high-quality nutraceuticals and supplements to the pharmaceutical, food, nutraceutical and cosmetics industries, Ogu Biotech has harnessed the power of grape skin extract and incorporated it into its product line.

The biochemical and pharmacological activities of grape skin extracts have been extensively studied. The content of polyphenols in the skin of red grape is 25% ~ 50%, mainly anthocyanins, resveratrol and flavonoids. Grape skin red is anthocyanin pigment. Its main coloring components are malvidin (malvidin chemicalbook), peonidin (peonidin), delphinidin (delphinidin) and the glucoside of 3 ‘-methylate (petunidin) or cyanidin (cyanidin). These findings highlight that grape skin extract is one of the most potent antioxidants available, making it an excellent choice for fighting free radicals and inhibiting lipid peroxidation. Grape skin extract is also a very good antioxidant and anti-aging substance, which is very good in effect, and has high efficiency biological activity, so it can further delay the aging of the skin, such as some women who love beauty, through such extracts, it can also resist the aging of the skin, make the skin become younger, smoother, and restore the young state. By scavenging free radicals, grape skin extract protects body cells from oxidative stress, thereby reducing the risk of various chronic diseases. Grape skin extract is rich in polyphenols, a group of antioxidants known for their numerous health benefits that offer a variety of benefits. One of its significant benefits is its potential to support cardiovascular health. Research shows that consuming grape skin extract can help lower blood pressure, lower bad cholesterol levels and improve overall heart function. These effects are attributed to the extract’s ability to enhance blood flow, reduce inflammation, and prevent the formation of blood clots.

In addition, grape skin extract has anti-inflammatory properties, making it an ideal natural solution for people suffering from chronic inflammation. By inhibiting the production of pro-inflammatory molecules, grape skin extract can reduce inflammation and its associated symptoms, thereby relieving and improving overall quality of life. Grape skin extract has been linked to promoting brain health and cognitive function. The high concentration of antioxidants in grape skin extract can protect brain cells from damage caused by oxidative stress and support memory retention and cognitive processes. Multiple studies have shown that regular consumption of grape skin extract can reduce the risk of age-related cognitive decline and neurodegenerative diseases such as Alzheimer’s disease.


Julyherb understands the importance of using the highest quality ingredients in its products. Our supplements use grape skin extract powder as a key ingredient, harnessing the full potential of this natural medicine. Through careful extraction techniques, the beneficial properties of the extracts are retained to provide quality products that promote optimal health and wellness.

Julyherb grape skin powder preparation method:

  • (1) Wash, dry and crush the skins of red grapes (through a 40-mesh sieve) for reserve use.
  • (2) Take 1000 grams of red grape skin powder, add 5000 grams of 50% ethanol, and stir and leach at 50 ~ 70Chemicalbook℃ for 1 ~ 2 hours after filtration.
  • (3) After filtration, the filter residue is then leached with 50% ethanol 5000 grams, under the same conditions, and after filtration, the filtrate is combined twice.
  • (4) The combined filtrate is evaporated and concentrated under reduced pressure, and ethanol is recovered at the top of the tower. Get the pigment from the bottom of the tower.
  • (5) After filtering the pigment liquid, it is continuously flowing from top to bottom at the rate of 2 ml per minute through a columnar tower with an inner diameter of 3 cm and equipped with a large pore adsorption resin. Grape red pigment was adsorbed by macroporous resin. Chemicalbook then washes the adsorption column with water until the effluent is colorless.
  • (6) The pigment is desorbed from the adsorption column to 95% ethanol by using 95% ethanol to flow from top to bottom through the column containing the adsorption resin at the same speed.
  • (7) The ethanol was recovered by vacuum evaporation, and the concentrated pigment liquid was obtained from the tower kettle, and the grape skin pigment powder was prepared after vacuum drying.

Grape skin extract can not only be added to cosmetics or nutritional health products, of course, can be applied to the food industry, wine juicing grape skin is the raw material source of grape skin pigment, extracted grape skin pigment can be widely used in fruit wine, jam, beverage coloring.

If you want to purchase high-quality grape skin extract powder, please consult Keira for details before ordering.